Flamboyant seafarer Jack Sparrow (Johnny Depp) lands himself in a bit of a bind after being lured onto Blackbeard's (Ian McShane) ship by enigmatic siren Angelica (Penélope Cruz), and forced to seek out the Fountain of Youth. Trapped on the Queen Anne's Revenge with the most nefarious pirate in history, Captain Jack reflects on his past with the elusive Angelica while embarking on his wildest adventure to date.